A 54‑year‑old woman presents with chest discomfort and mild dyspnea. Her ECG shows ST elevation in V2–V3. A clinician diagnoses “STEMI” and activates the cath lab.

A second clinician reviews the ECG and notes:

  • Upward concavity
  • J‑point notching
  • Stable morphology compared to a prior ECG
  • No reciprocal changes
  • Normal hemodynamics

The correct diagnosis is early repolarization, not acute occlusion.

Mechanism‑Based Reasoning

Early repolarization is a benign variant caused by:

  • Increased vagal tone
  • Enhanced phase 1 repolarization
  • J‑point elevation

Understanding the mechanism prevents misdiagnosis (for a more complete discussion, see Getting Acquainted With Ischemia and Infarction).

The Teaching Point

Pattern‑based learning encourages clinicians to equate “ST elevation” with “STEMI.” Mechanism‑based learning teaches clinicians to analyze:

  • Morphology
  • Context
  • Stability
  • Reciprocal changes
  • Clinical presentation

This prevents unnecessary interventions.

Conclusion

This case illustrates how pattern‑based errors lead to unnecessary procedures, while mechanism‑based reasoning leads to accurate diagnosis.

For a curated overview of the most frequent ECG interpretation errors, see: Top 10 ECG Mistakes Clinicians Still Make.