Jones’s Rule: Rethinking ST‑Segment Depression as Reciprocal Change in Acute Coronary Syndromes
For decades, clinicians have been taught to interpret ST‑segment depression as a marker of subendocardial ischemia. While that framework is sometimes correct, it is also responsible for one of the most persistent diagnostic blind spots in acute coronary syndromes: the failure to recognize reciprocal ST‑segment changes as evidence of an evolving transmural ischemia, or STEMI. […]